By Kathryn Doyle (Reuters Health) – A large weight loss, even if regained, may help overweight people with type 2 diabetes improve their blood sugar control and cholesterol and lower high blood pressure long-term, a new study suggests. Over four years, even those who regained all of a large weight loss had greater improvements in blood sugar than their counterparts who lost no weight or initially lost a smaller amount. “Since many people lose weight and regain some (or all) of it, it is important to know whether this pattern leads to better or worse outcomes than never losing weight,” said coauthor Rena Wing, a professor of psychiatry and human behavior at The Warren Alpert Medical School of Brown University.